Anticoagulant and Antithrombotic Drugs: Nursing Considerations

Anticoagulant and Antithrombotic Drugs: Nursing Considerations 

Nurses providing care to both inpatient and outpatient populations currently face greater complexity in the drug regimens that patients present with than ever before. The role of the clinician includes recognition of risk, as well as identification of interactions that are manifest. Emphasis will be placed on recognition of the potential for untoward interactions, including operant mechanisms, as well as on the identification of strategies to ensure patient safety.


Hours: 1.25


Certificates provided by accrediting body (0 Match)

Course Details

Course Code: REL-PAC-0-AADNC
Hours: 1.25
Type: Online Course
Content Expiration Date: 5/31/2023
Learning Objectives:
Compare the mechanism of action of heparin, low molecular weight heparin (LMWH), warfarin, thrombin inhibitors, and factor Xa inhibitors.
Compare the mechanisms of action of the antiplatelet drugs, aspirin (ASA), adenosine diphosphate (ADP) blocking agents, and the glycoprotein (GP)IIb/IIIa receptor antagonists.
Describe the differences between the processes of arterial and venous thrombi development.
Describe the mechanisms of action, recommended uses, and adverse reactions commonly associated with thrombolytic drugs.
List at least three common indications for the administration of anticoagulants.
Describe at least three differences between direct-acting oral anticoagulants and warfarin.


Section 1: Introduction

About This Course

Learning Objectives

Section 2: Terminology and Physiology


Blood Clot Formation Sequence

Indications for Anticoagulant Use



Section 3: Heparin


Monitoring Heparin

Low Molecular Weight Heparin

Advantages of LMWH Over Heparin

Complications of Heparin

Synthetic Pentasaccharide



Section 4: Warfarin

Warfarin Indications

Mechanism of Action

Dosing and Monitoring

Warfarin Contraindications

Warfarin Drug Interactions

Herb and Supplement Interactions

Food Interactions



Section 5: Newer Oral Anticoagulants

Thrombin Inhibitors

Factor Xa Inhibitors



Section 6: Antiplatelet Drugs


ADP Blockers

Glycoprotein Platelet Inhibitors

Adverse Reactions/Precautions



Section 7: Thrombolytic Drugs

Contraindication and Interactions



Section 8: Conclusion


Course Contributors


Instructor: Kim Matthews, RN
Kimberly Matthews, RN obtained a nursing degree from Western Kentucky University in 1998.  Ms. Matthews possesses over 20 years of nursing experience with over 17 of those in the Skilled Nursing industry.  Ms. Matthews has extensive experience in MDS, restorative nursing programs, and nursing management.  Ms. Matthews is currently a Post Acute Care Content writer and subject matter expert for MDS. Disclosure: Kim Matthews, RN has declared that no conflict of interest, Relevant Financial Relationship or Relevant Non-Financial Relationship exists.
Expert Reviewer: Adam Root, PharmD
Adam Root graduated from the University of Pittsburgh with a Doctor of Pharmacy degree in 2013. Adam has worked in the managed care, medication policy, drug information, and community pharmacy settings and has a background in policy and guideline development, clinical program design, and medication use evaluation. He is currently employed as a Clinical Pharmacist in the Formulary Management Department at PerformRx. Adam's primary area of interest is utilizing evidence-based medicine to improve the efficacy, safety, and cost of healthcare. Disclosure: Adam Root, PharmD has declared that no conflict of interest, Relevant Financial Relationship or Relevant Non-Financial Relationship exists.
Target Audience:
The target audience for this course is: Nurses; in the following settings: Post-Acute Care.
Relias will be transparent in disclosing if any commercial support, sponsorship or co-providership is present prior to the learner completing the course.
Course Delivery Method and Format
Asynchronous/Online Distance Learning; please see certificate details for specifics on delivery format.
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