Antipsychotic Medications and Their Adverse Reactions

Outline:
Section 1: Introduction

About This Course

Learning Objectives

Section 2: Psychotic Mental Disorders

Psychosis

Disorganized Speech Schizophrenia

Bipolar Disorder

The Dopamine Hypothesis

Antipsychotics

Summary

Section 3: First-Generation Antipsychotics

Typical Antipsychotics: Phenothiazine Derivatives

Other First-Generation Agents

Summary

Section 4: Second-Generation Antipsychotics

Atypical Antipsychotics

Partial Dopamine Agonists

Benefits of Injection

Drug Interactions

Black Box Warning

Summary

Section 5: Side Effects of Antipsychotics

Mechanisms for Adverse Effects

Adverse Effects

Neuromotor Adverse Effects

Hyperprolactinemia

Weight Gain

Metabolic Syndrome

QTc Prolongation

Orthostatic Hypotension

Stroke and Coronary Heart Disease

Myocarditis and Cardiomyopathy

Neuroleptic Malignant Syndrome

Summary

Section 6: Additional Side Effects and Organ Dysfunction

Further Side Effects

Organ Dysfunction

Summary

Section 7: Clinical Vignette

Meet Gloria

Section 8: Conclusion

Course Summary

Course Contributors

References

Sean Kennard is an Air Force veteran with 10 years of active-duty service plus clinical experience in various mental health settings. Sean was educated and trained In Virginia as a Registered Nurse, where he practiced pediatric behavioral health nursing at Cumberland Hospital for Children and Adolescents in New Kent. He earned his Associate’s Degree in Nursing from ECPI University and Bachelor of Science in Nursing from Western Governors University. Sean is a former Program Director of a Senior Behavioral Health Unit and currently coaches licensure exam strategies to nursing graduates. His clinical skillset is in behavioral health across the lifespan, including behavioral case management and geropsychiatric nursing. He most recently worked as a Forensic Psych Nurse at Central State Hospital in Georgia during the onset of the pandemic before contracting with Relias as a Behavioral Health Subject Matter Expert Technical Writer. Disclosure: Sean Kennard BSN, RN has no Relevant Financial or Non-Financial Relationship with ineligible companies to disclose.

Ms. Workman is an Instructional Designer at Relias. She has a Master of Arts in Technology and Communication, as well as graduate certificates in Public Health, Epidemiology, and Digital Communications. Ms. Workman has a background in writing and designing online continuing medical education for physicians and other health professionals on multiple educational platforms, including web-based, game-based, and immersive learning environments. She has also used simulation training extensively to connect learning to real-world environments. Disclosure: Kimberly Workman, MA discloses the following potential conflict of interests/commercial interests: Relevant Financial Relationship with Relias LLC as a Salaried Employee All of the relationships listed for this individual have been mitigated.Relevant Non-Financial Relationship with No Entities Exists as a Contributor All of the relationships listed for this individual have been mitigated.