Von Willebrand disease (vWD) is the most common inherited genetic bleeding disorder, yet it is not well known or understood among the public or healthcare providers. Von Willebrand factor (vWF) is a protein that is essential for platelet aggregation and clotting. A low vWF can lead to heavy or prolonged bleeding. This most commonly appears as complaints of menorrhagia (i.e., heavy menstrual bleeding), prolonged bleeding after minor injuries, or gum bleeding. The clinician can advocate for proper diagnosis and treatment, as well as prevent adverse events by being aware of the presenting signs and types of the disorder, recognizing that many patients are asymptomatic, and understanding when a hematology consultation is warranted.
Section 1: Introduction
About This Course
Section 2: Understanding von Willebrand Disease
Hemostasis and von Willebrand Factor
Section 3: Clinical Vignette
Section 4: Conclusion
Expert Reviewer: Christopher Reist, MD, MBA
Nicole Strickland, BA, BSN, RN, CPAN has cared for patients at every level of acuity over almost 10 years as a nurse. She has devoted much of her nursing career to training nurses and nursing students as a Certified Post Anesthesia Nurse (CPAN). She holds a BA in English from Temple University and worked as a medical editor for the National Board of Medical Examiners before returning to school to obtain a BSN from Duke University. She is now pursuing a Master of Education in Learning Design and Technology from The University of North Carolina at Charlotte while continuing her passion for the creation of evidenced-based and engaging education as an acute care SME writer at Relias.Disclosure: Nicole Strickland, BA, BSN, RN, CPAN has declared that no conflict of interest, Relevant Financial Relationship or Relevant Non-Financial Relationship exists.
Dr. Reist is Professor Emeritus in the Department of Psychiatry and Human Behavior at the University of California, Irvine. He has served as Assistant Dean in the College of Medicine and the Director of Medical Research for the Long Beach Veterans Affairs Healthcare System. Formerly, he served as Chief of Mental Health, overseeing full service mental health care delivery to over 50,000 enrollees at the Long Beach VA Healthcare System. He was the Associate Director of the Southern California VA Mental Illness Research, Education, and Clinical Center (MIRECC), which is focused on improving long-term outcomes in chronic psychotic disorders through basic/clinical research and dissemination of evidence-based practices. Dr. Reist’s clinical interests include schizophrenia, impulsivity, PTSD, pharmacogenomics, and psychopharmacology. DoD, NIMH, and VA Medical Research have supported his research. Dr. Reist is a Distinguished Fellow of the Psychiatric Association, has been recognized as an Exemplary Psychiatrist by the National Alliance for the Mentally Ill, and is included in Best Doctors 2007-2019. He is the author of two books and over 75 original scientific articles. Disclosure: Christopher Reist, MD, MBA discloses the following potential conflict of interests/commercial interests: Relevant Financial Relationship with Alkermes as Grant/Research Support Relevant Non-Financial Relationship with No Entities Exists as a ContributorExpert Reviewer: Catherine J. Swift, MT(ASCP)
Catherine Swift, MT(ASCP) is the clinical laboratory science editor for Relias Learning. She has a Bachelor of Arts in English from Hastings College and a Bachelor of Science in Medical Technology from North Colorado Medical Center. She has experience working in hospital laboratories, clinic laboratories, and research experience in microbiology as well as clinical research trials involving patients and various drug therapies for osteoporosis, endometriosis and bone density at Creighton University School of Medicine. Disclosure: Catherine J. Swift, MT(ASCP) has declared that no conflict of interest, Relevant Financial Relationship or Relevant Non-Financial Relationship exists.
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