Acetaminophen Overdose and Management
Hours: 1.00
Acetaminophen toxicity is the most frequent cause of emergency calls to poison control centers and of acute liver failure in the U.S. Contributing factors include medication errors, OTC availability, and inadequate patient education. Overdose must be treated as quickly as possible to avoid acute liver failure or death. Patients who receive N-acetylcysteine treatment within the first 8 hours of overdose have a very positive prognosis with less than a 5% chance of developing liver toxicity. Delays in treatment beyond 10 hours lead to a poorer prognosis. Pharmacists need to be aware of the recommended doses for acetaminophen use, signs and symptoms of acute liver injury, and emergency treatment protocols.
Acetaminophen toxicity is the most frequent cause of emergency calls to poison control centers and of acute liver failure in the U.S. Contributing factors include medication errors, OTC availability, and inadequate patient education. Overdose must be treated as quickly as possible to avoid acute liver failure or death. Patients who receive N-acetylcysteine treatment within the first 8 hours of overdose have a very positive prognosis with less than a 5% chance of developing liver toxicity. Delays in treatment beyond 10 hours lead to a poorer prognosis. Pharmacists need to be aware of the recommended doses for acetaminophen use, signs and symptoms of acute liver injury, and emergency treatment protocols.
Accreditation Council for Pharmacy Education
In support of improving patient care, Relias LLC is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.
Type Activity: Knowledge
Target Audience Designation: P
ACPE Universal Activity Number: JA4008266-0000-21-155-H04-P
Accreditation Council for Pharmacy Education
In support of improving patient care, Relias LLC is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.
Type Activity: [Custom_Code]
Target Audience Designation: [Custom_Code2]
ACPE Universal Activity Number: JA4008266-0000-21-155-H04-T
Florida Board of Pharmacy
Florida Board of Pharmacy (CEBroker Provider #50-290)
This module is approved for 1.00 contact hours.
Identify the various causes of acetaminophen overdose.
Describe the latest dosing recommendations for and formulations containing acetaminophen.
Explain treatment protocols and management techniques for acetaminophen overdose.
Outline:
Section 1: Introduction
About This Course
Learning Objectives
Section 2: Acetaminophen Overdose and Management
Background
Patient Education
Pathophysiology of Toxicity
Dosage and Toxicity
Lab Values to Analyze
Acute Liver Failure
Risk Factors
GI Decontamination
Treatment
Antiemetics
NAC
Repeated Supratherapeutic Acetaminophen Levels in Context of Massive Consumption
Consultation
Summary
Section 3: Clinical Vignette
Meet Conrad
Section 4: Conclusion
Summary
Course Contributors
References
Subject Matter Expert: Shana Jiang, PharmD, BCPSSooa Devereaux, MSN, RN, has a long history of professional development experience within the hospital setting. She has taught in pre-licensure nursing programs and has mentored many nurses, both new graduate and experienced, throughout her career as a nurse educator. Sooa is a Lead SME Writer at Relias and holds an MSN in Nursing Education.
Disclosure: Sooa Devereaux, MSN, RN has no Relevant Financial or Non-Financial Relationship with ineligible companies to disclose.
Shana Jiang, PharmD, BCPS, received her Doctor of Pharmacy degree in 2014 from the Ernest Mario School of Pharmacy at Rutgers University and completed a pharmacy practice residency with Mount Sinai St. Luke's and Roosevelt Hospitals in New York, NY. She is now working as a telepharmacist for a major health system.
Disclosure: Shana Jiang, PharmD, BCPS has no Relevant Financial or Non-Financial Relationship with ineligible companies to disclose.
The target audience for this course is: Pharmacists; Pharmacy Technicians; in the following settings: Acute Care Facility.
Asynchronous/Online Distance Learning; please see certificate details for specifics on delivery format.
Relias has a grievance policy in place to facilitate reports of dissatisfaction. Relias will make every effort to resolve each grievance in a mutually satisfactory manner. In order to report a complaint or grievance please contact Relias.
If you require special accommodations to complete this module, please contact Relias Support by completing the web form (https://www.relias.com/help) or by using the chat functionality.
All courses offered by Relias, LLC are developed from a foundation of diversity, inclusiveness, and a multicultural perspective. Knowledge, values and awareness related to cultural competency are infused throughout the course content.
Reference herein to any specific commercial product, process, or service by trade name, trademark, service mark, manufacturer or otherwise does not constitute or imply any endorsement, recommendation, or favoring of, or affiliation with, Relias, LLC.
All characteristics and organizations referenced in the following training are fictional. Any resemblance to any actual organizations or persons living or dead, is purely coincidental.
To earn continuing education credit for this course you must achieve a passing score of 80% on the post-test and complete the course evaluation.
If you require special accommodations to complete this module, please contact Relias Customer Support here.
