Traditionally, the treatment of individuals at risk for suicide has emphasized the person’s primary psychiatric disorder as the focus of treatment. The rationale was that as the person’s psychiatric disorder improved, they would feel less suicidal. Current guidelines based on the accumulation of evidence about treatment efficacy indicates that this approach is insufficient (The Joint Commission, 2016). The data on suicide rates in the U.S. support the need for improved identification and treatment of at-risk individuals. In 2018 alone, over 48,000 people died by suicide, and there were another 1.4 million attempts (Xu et al., 2020). Gaps in training programs have resulted in clinicians lacking exposure to effective methods to identify and treat suicidal individuals (Brodsky et al., 2018). At the organizational level, routine implementation of evidence-based practices that can identify and intervene with at-risk individuals has been lacking for many years and remains so in many settings. The goal of this course is to provide alcohol and drug counseling, nursing, counseling, psychology, and social work professionals in health and human services with knowledge about evidence-based, suicide-specific interventions. Note: This course covers suicide-specific interventions with adults. Please review the other available courses on suicide prevention in the Relias library for content on risk factors, screening, assessment, postvention, and working with suicidal adolescents.